Immunity- reactions that occur in responce to a pathogen or disease causing organsim The immune system has three lines of defence. 1. Physical and chemical barriers. 2. Innate responces 3. Specific responces
Class I markers are a group of proteins produced by a set of genes called the major histocompatibility complex MHC and are found on the membranes of all true cells- red blood cells are not true cells; one of the self proteins of an individual. Class I markers are detected by T-cells and appear abnormal in cancerous or viral infected cells. Abnormal proteins or sugars are found on these MHC proteins when the cells are not functioning correctly. Class II markers are found only on the surface of B-cells T- cells and some macrophages. Class II markers or MHCII complexes are involved in antigen presentation. When foreign antigens are detected they are cut up within the cell attached to an MHCII complex and displayed on the cells surface for cellular recognition.
self and non self -MHC markers
a group of proteins produced by a set of genes called the major histocompatibility complex Class I markers are found on the membranes of all true cells Class II markers are found on the membranes of B and T lymphocytes and some macrophages and dentritic cells