Welcome to E2 Reactions Made Easy!
By: Joanna Grant, Alexis McLean, & Jessica Watts
What is an elimination reaction?
A halogen is removed from one carbon A hydrogen is removed from an adjacent carbon A double bond is formed between the two carbons where the atoms were eliminated. The product of an elimination reaction is an alkene
Two Types of Elimination Reactions
An E1 reaction is unimolecular rate=k[R-X] and stepwise with a C+ intermediate A base removes a H+ from the beta carbon then the leaving group leaves on its own.
An E2 reaction is biomolecular rate=k[R-X][base] and concerted. A base removes a H+ from the beta carbon at the same time the leaving group leaves.
We'll focus on E2!
What are Elimination Reactions
3. Alkyl Halide
1. Beta hydrogen
Book Name here
An E2 Reaction
Competition between E1 & E2
3 Main Differences
1. Degree of saturation 2. Base strength 3. Solvent used
When E2 is favored over E1 :
1. Primary and secondary (controversial) saturated alkyl halide 2. Stong base (OH or better) 3. Polar aprotic Solvent